Is PHA-738144 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use PHA-738144? Is PHA-738144 safe for nursing mother and child? Does PHA-738144 extracts into breast milk? Does PHA-738144 has any long term or short term side effects on infants? Can PHA-738144 influence milk supply or can PHA-738144 decrease milk supply in lactating mothers?
PHA-738144 lactation summary
- DrLact safety Score for PHA-738144 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of PHA-738144 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that PHA-738144 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of PHA-738144 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About PHA-738144 usage in lactation
Monoclonal antibody directed against TNF (tumoral necrosis factor) that is used for treatment of autoimmune diseases like Rheumatoid Arthritis and Crohn's Disease. Probably because of a high molecular weight, no detectable traces have been found in mother's milk. It is not absorbed by the gut which is even more protective for the nursing infant. No harm effect has been shown among breastfed infants whose mothers were treated with this medication. Avoid using it in the two post-partum weeks since significant excretion into the milk within the first 3 - 4 days after delivery and absorption by the infant is possible.