Question

I am a breastfeeding mother and i want to know if it is safe to use Chloramiphene Citrate? Is Chloramiphene Citrate safe for nursing mother and child? Does Chloramiphene Citrate extracts into breast milk? Does Chloramiphene Citrate has any long term or short term side effects on infants? Can Chloramiphene Citrate influence milk supply or can Chloramiphene Citrate decrease milk supply in lactating mothers?

Chloramiphene Citrate lactation summary

Chloramiphene Citrate usage has low risk in breastfeeding
  • DrLact safety Score for Chloramiphene Citrate is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Chloramiphene Citrate may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Chloramiphene Citrate may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Chloramiphene Citrate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Chloramiphene Citrate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Chloramiphene Citrate usage in lactation

Synthetic ovulation stimulant. It inhibits hypothalamic estrogen receptors, which in turn stimulates the release of FSH, estradiol and LH. It has initially anti-estrogenic and then estrogenic effects.Indicated to induce ovulation in infertility treatment and polycystic ovary syndrome (Hossein 2016, AEMPS 2016, Sanofi 2012, López 2004, Sheehan 2004, Kousta 1997).Increased risk of multiple pregnancy. Administered orally, a daily dose for 5 days, maximum 3 menstrual cycles. Since the last update, we have not found published data on its excretion in breast milk. Its high volume of distribution makes the transfer to milk in significant quantities unlikely, but its long half-life could facilitate it. Adverse effects are infrequent and temporary at usual doses; they occur in high doses and for prolonged periods such as those used in research studies (AEMPS 2016, Sanofi 2012). Studies on the effects on prolactin and milk production are scarce, out of date and contradictory, for while for some authors clomiphene decreases prolactin plasma levels, inhibiting breastfeeding when administered during the first week postpartum (Weinstein 1976, Kalir 1975), for others it has no effect on prolactin nor does it inhibit breastfeeding (Canales 1977). In any case, when breastfeeding is well established, prolactin levels do not correlate with milk production. This would be the case in an infertility treatment. It is not advisable to take it during the first weeks of the postpartum period due to the risk of decreased milk production. In infertility treatment, the possible anovulatory effect of frequent on demand breastfeeding should be taken into account. See below the information of these related products:
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.