Is N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol? Is N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol safe for nursing mother and child? Does N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol extracts into breast milk? Does N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol has any long term or short term side effects on infants? Can N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol influence milk supply or can N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol decrease milk supply in lactating mothers?
N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol lactation summary
- DrLact safety Score for N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol usage in lactation
At latest update, relevant published data on excretion into breast milk were not found. Because of high serum protein-binding capacity, excretion into breast milk in significant amount is seemingly unlikely. It is a metabolite of Bromhexine. Known adverse reactions are rare and mild. Authorized for use in children. Secretion of Prolactin and other hormones have not been affected by taking this medication. Effectiveness of this drug has not been established.
Alternate Drugs for Mucolytics & Expectorants. ATC R05C
Guaifenesin(Low Risk)
Dornase Alfa(Safe)
Iodopropylidene-Glycerol(Unsafe)
Ambroxol(Safe)
Bromhexine(Safe)
Carbocisteine(Safe)
Erdosteine(Safe)
Carbocysteine(Safe)
Guaiacol Glycerol Ether(Low Risk)