Question

I am a breastfeeding mother and i want to know if it is safe to use Bromhexine-metabolite VIII? Is Bromhexine-metabolite VIII safe for nursing mother and child? Does Bromhexine-metabolite VIII extracts into breast milk? Does Bromhexine-metabolite VIII has any long term or short term side effects on infants? Can Bromhexine-metabolite VIII influence milk supply or can Bromhexine-metabolite VIII decrease milk supply in lactating mothers?

Bromhexine-metabolite VIII lactation summary

Bromhexine-metabolite VIII is safe in breastfeeding
  • DrLact safety Score for Bromhexine-metabolite VIII is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Bromhexine-metabolite VIII is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Bromhexine-metabolite VIII does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Bromhexine-metabolite VIII safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Bromhexine-metabolite VIII usage in lactation

At latest update, relevant published data on excretion into breast milk were not found. Because of high serum protein-binding capacity, excretion into breast milk in significant amount is seemingly unlikely. It is a metabolite of Bromhexine. Known adverse reactions are rare and mild. Authorized for use in children. Secretion of Prolactin and other hormones have not been affected by taking this medication. Effectiveness of this drug has not been established.

Alternate Drugs for Mucolytics & Expectorants. ATC R05C

Guaifenesin(Low Risk)
Dornase Alfa(Safe)
Iodopropylidene-Glycerol(Unsafe)
Ambroxol(Safe)
Bromhexine(Safe)
Carbocisteine(Safe)
Erdosteine(Safe)
Carbocysteine(Safe)
Guaiacol Glycerol Ether(Low Risk)

Synonyms of Bromhexine-metabolite VIII

Ambroxolum [INN-Latin]
trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol [Spanish]
trans-4-((2-Amino-3,5-dibromobenzyl)amine)cyclohexanol
N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol [Spanish]
N-(2-Amino-3,4-dibromocyclohexyl)-trans-4-aminocyclohexanol
Bisolvon metabolite VIII
EINECS 242-500-3
N-(trans-4-Hidroxiciclohexil)-(2-amino-3,5-dibromobencil)amina [Spanish]
N-(trans-p-Hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)amine
N-(trans-4-Hydroxycyclohexyl)-(2-amino-3,5-dibromobenzyl)-amine
NA-872
Ambroxolum
N-(2-Amino-3,4-dibromociclohexil)-trans-4-aminociclohexanol
N-(trans-4-Hidroxiciclohexil)-(2-amino-3,5-dibromobencil)amina
trans-4-((2-Amino-3,5-dibromobencil)amino)ciclohexanol
UNII-200168S0CL
EC 242-500-3
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.