Is 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone? Is 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone safe for nursing mother and child? Does 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone extracts into breast milk? Does 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone has any long term or short term side effects on infants? Can 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone influence milk supply or can 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone decrease milk supply in lactating mothers?
1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone lactation summary
- DrLact safety Score for 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1-(10-(3-(4-(2-Hydroxyethyl)-1-piperazinyl)propyl)phenothiazin-2-yl)-1-propanone usage in lactation
It is a tranquillizer similar to prochlorperazine that may produce galactorrhea by increasing prolactin level. No data on transfer into breastmilk are available. Not commercially available in Spain
Alternate Drugs for Anti-psychotics Phenotiazines
Chlorpromazine(Low Risk)
Fluphenazine(Low Risk)
Mesoridazine(Unsafe)
Perphenazine(Safe)
Prochlorperazine(Unsafe)
Thioridazine(Unsafe)
Trifluoperazine(Safe)
Acetophenazine(Unsafe)
Butaperazine(Unsafe)
Carphenazine(Low Risk)
Levomepromazine(Unsafe)
Periciazine(Unsafe)
Pipotiazine(Unsafe)
Thioproperazine(Unsafe)
Triphthazine(Safe)
Perfenazina(Safe)
Methotrimeprazine(Unsafe)
Tioproperazina(Unsafe)