Is Gliclazidum [INN-Latin] Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Gliclazidum [INN-Latin]? Is Gliclazidum [INN-Latin] safe for nursing mother and child? Does Gliclazidum [INN-Latin] extracts into breast milk? Does Gliclazidum [INN-Latin] has any long term or short term side effects on infants? Can Gliclazidum [INN-Latin] influence milk supply or can Gliclazidum [INN-Latin] decrease milk supply in lactating mothers?

Gliclazidum [INN-Latin] lactation summary

Gliclazidum [INN-Latin] usage has low risk in breastfeeding

DrLact safety Score for Gliclazidum [INN-Latin] is 3 out of 8 which is considered Low Risk as per our analyses.
A safety Score of 3 indicates that usage of Gliclazidum [INN-Latin] may cause some minor side effects in breastfed baby.
Our study of different scientific research indicates that Gliclazidum [INN-Latin] may cause moderate to no side effects in lactating mother.
Most of scientific studies and research papers declaring usage of Gliclazidum [INN-Latin] low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
While using Gliclazidum [INN-Latin] We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Gliclazidum [INN-Latin] usage in lactation

Sulfonilurea drugs stimulate secretion of endogen insulin. Oral anti-diabetic drugs are useless for treatment of diabetes type 1. For diabetes type 2, diet and exercise are advisable. Breastfeeding helps to lower glucemia level. See section on Maternal diabetes mellitus

Alternate Drugs for Oral blood glucose lowering drug (Anti-diabetic). Sulfonamide, urea derivative. ATC A10BB

Acetohexamide(Low Risk)

Chlorpropamide(Low Risk)

Glimepiride(Unsafe)

Glipizide(Safe)

Glyburide(Safe)

Tolbutamide(Safe)

Glibenclamide(Safe)

Gliclazide(Low Risk)

Synonyms of Gliclazidum [INN-Latin]

S 1702

S 852

1-(3-Azabicyclo(3.3.0)oct-3-yl)-3-(p-tolylsulfonyl)urea

Benzenesulfonamide, N-(((hexahydrocyclopenta(c)pyrrol-2(1H)-yl)amino)carbonyl)-4-methyl-

BRN 1657836

Diamicron

EINECS 244-260-5

Gliclazida [INN-Spanish]

Glimicron

1-(Hexahydrocyclopenta(c)pyrrol-2(1H)-yl)-3-(p-tolylsulfonyl)urea

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.