I am a breastfeeding mother and i want to know if it is safe to use Cimetidine? Is Cimetidine safe for nursing mother and child? Does Cimetidine extracts into breast milk? Does Cimetidine has any long term or short term side effects on infants? Can Cimetidine influence milk supply or can Cimetidine decrease milk supply in lactating mothers?

Cimetidine lactation summary

Cimetidine usage has low risk in breastfeeding
  • DrLact safety Score for Cimetidine is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Cimetidine may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Cimetidine may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Cimetidine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Cimetidine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Cimetidine usage in lactation

No long-term adverse effects have been reported. However, it is excreted in large amounts into breast milk. American Academy of Pediatrics: Maternal Medication Usually Compatible With Breastfeeding.

Answer by DrLact: About Cimetidine usage in lactation

Limited information indicates that maternal cimetidine results in infant dosages much less than those given directly to neonates. Cimetidine would not be expected to cause any adverse effects in breastfed infants, especially if the infant is older than 2 months. However, because of its potential for causing hepatic enzyme inhibition, other drugs might be preferred.

Cimetidine Possible Effects in Breastfeeding

Histamine H2-receptor blockade is known to stimulate prolactin secretion. In addition, cimetidine may have additional, nonspecific actions that stimulate prolactin secretion.[2] Oral cimetidine doses of 400 mg 4 times daily increased serum prolactin by 50 to 112% in 6 patients. Cimetidine caused dose-related gynecomastia and galactorrhea in men and nonnursing women.[3][4][5] The prolactin level in a mother with established lactation may not affect her ability to breastfeed.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.