Is 1-(4-Chlorobenzhydryl)-4-methylpiperazine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-(4-Chlorobenzhydryl)-4-methylpiperazine? Is 1-(4-Chlorobenzhydryl)-4-methylpiperazine safe for nursing mother and child? Does 1-(4-Chlorobenzhydryl)-4-methylpiperazine extracts into breast milk? Does 1-(4-Chlorobenzhydryl)-4-methylpiperazine has any long term or short term side effects on infants? Can 1-(4-Chlorobenzhydryl)-4-methylpiperazine influence milk supply or can 1-(4-Chlorobenzhydryl)-4-methylpiperazine decrease milk supply in lactating mothers?
1-(4-Chlorobenzhydryl)-4-methylpiperazine lactation summary
- DrLact safety Score for 1-(4-Chlorobenzhydryl)-4-methylpiperazine is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1-(4-Chlorobenzhydryl)-4-methylpiperazine may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1-(4-Chlorobenzhydryl)-4-methylpiperazine may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1-(4-Chlorobenzhydryl)-4-methylpiperazine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1-(4-Chlorobenzhydryl)-4-methylpiperazine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1-(4-Chlorobenzhydryl)-4-methylpiperazine usage in lactation
It is a first generation anti-histaminic and piperazine drug with a moderate sedative effect. Commercialized in association with other drugs for coughing relief and expectorant compounds. Overall, avoid drug associations especially while breastfeeding.
Alternate Drugs for Antihistamines for systemic use. ATC R06A.
Acrivastine(Low Risk)
Brompheniramine(Low Risk)
Carbinoxamine(Low Risk)
Cetirizine(Safe)
Chlorpheniramine(Low Risk)
Clemastine(Low Risk)
Desloratadine(Safe)
Dexchlorpheniramine(Low Risk)
Dimenhydrinate(Low Risk)
Diphenhydramine(Low Risk)
Fexofenadine(Safe)
Hydroxyzine(Safe)
Loratadine(Safe)
Promethazine(Low Risk)
Pyrilamine(Low Risk)
Thiethylperazine(Unsafe)
Triprolidine(Safe)
Epinastine(Low Risk)
Meclizine(Low Risk)
Ketotifen(Low Risk)
Levocetirizine(Low Risk)
Cyclizine(Low Risk)
Doxylamine(Unsafe)
Cetirizine Hydrochloride(Safe)
Alimemazine(Low Risk)
Astemizole(Unsafe)
Azatadine Maleate(Low Risk)
Bilastine(Low Risk)
Brompheniramine Maleate(Low Risk)
Buclizine-Hcl(Low Risk)
Carbinoxamine Maleate(Low Risk)
Cyproheptadine-Hcl(Low Risk)
Clemastine Fumarate(Low Risk)
Chlorcyclizine(Low Risk)
Chlorphenamine(Low Risk)
Chloropyramine Hydrochloride(Unsafe)
Ebastine(Low Risk)
Ketotifen Fumarate(Low Risk)
Meclozine(Low Risk)
Mepyramine(Low Risk)
Mequitazine(Unsafe)
Mizolastine(Low Risk)
Pizotifen(Low Risk)
Rupatadine Fumarate(Low Risk)
Terfenadine(Low Risk)
Trimeprazine(Low Risk)
Halopyramine Hydrochloride(Unsafe)
Doxylamine Succinate(Unsafe)
Dramamine Ii(Low Risk)
Chlorpheniramine Maleate(Low Risk)
Pizotyline(Low Risk)
Benzhydramine(Low Risk)
Promethazine Hydrochloride(Low Risk)
Pyranisamine(Low Risk)
Kelp(Unsafe)