Is EINECS 228-216-2 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use EINECS 228-216-2? Is EINECS 228-216-2 safe for nursing mother and child? Does EINECS 228-216-2 extracts into breast milk? Does EINECS 228-216-2 has any long term or short term side effects on infants? Can EINECS 228-216-2 influence milk supply or can EINECS 228-216-2 decrease milk supply in lactating mothers?
EINECS 228-216-2 lactation summary
- DrLact safety Score for EINECS 228-216-2 is 5 out of 8 which is considered Unsafe as per our analyses.
- A safety Score of 5 indicates that usage of EINECS 228-216-2 may cause serious side effects in breastfed baby.
- Our study of different scientific research indicates that EINECS 228-216-2 may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using EINECS 228-216-2 .
- It is recommended to evaluate the advantage of not breastfeeding while using EINECS 228-216-2 Vs not using EINECS 228-216-2 And continue breastfeeding.
- While using EINECS 228-216-2 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About EINECS 228-216-2 usage in lactation
First generation antihistamine drug which is derived from ethylene diamine with important sedative and antimuscarinic effects. The anticholinergic effect may inhibit lactation. At latest update no published data on excretion into breast milk was found. Drug that is scarcely supported by bibliographical evidence, which is marketed in very few countries from Eastern Europe, Mexico ... Until more published information about this drug regarding breastfeeding appears, it may be preferable the use of a known and safer alternative.
Alternate Drugs for Antihistamines for systemic use. ATC R06A.
Acrivastine(Low Risk)
Brompheniramine(Low Risk)
Carbinoxamine(Low Risk)
Cetirizine(Safe)
Chlorpheniramine(Low Risk)
Clemastine(Low Risk)
Desloratadine(Safe)
Dexchlorpheniramine(Low Risk)
Dimenhydrinate(Low Risk)
Diphenhydramine(Low Risk)
Fexofenadine(Safe)
Hydroxyzine(Safe)
Loratadine(Safe)
Promethazine(Low Risk)
Pyrilamine(Low Risk)
Thiethylperazine(Unsafe)
Triprolidine(Safe)
Epinastine(Low Risk)
Meclizine(Low Risk)
Ketotifen(Low Risk)
Levocetirizine(Low Risk)
Cyclizine(Low Risk)
Doxylamine(Unsafe)
Cetirizine Hydrochloride(Safe)
Alimemazine(Low Risk)
Astemizole(Unsafe)
Azatadine Maleate(Low Risk)
Bilastine(Low Risk)
Brompheniramine Maleate(Low Risk)
Buclizine-Hcl(Low Risk)
Carbinoxamine Maleate(Low Risk)
Cyproheptadine-Hcl(Low Risk)
Clemastine Fumarate(Low Risk)
Chlorcyclizine(Low Risk)
Chlorphenamine(Low Risk)
Chloropyramine Hydrochloride(Unsafe)
Ebastine(Low Risk)
Ketotifen Fumarate(Low Risk)
Meclozine(Low Risk)
Mepyramine(Low Risk)
Mequitazine(Unsafe)
Mizolastine(Low Risk)
Pizotifen(Low Risk)
Rupatadine Fumarate(Low Risk)
Terfenadine(Low Risk)
Trimeprazine(Low Risk)
Halopyramine Hydrochloride(Unsafe)
Doxylamine Succinate(Unsafe)
Dramamine Ii(Low Risk)
Chlorpheniramine Maleate(Low Risk)
Pizotyline(Low Risk)
Benzhydramine(Low Risk)
Promethazine Hydrochloride(Low Risk)
Pyranisamine(Low Risk)
Kelp(Unsafe)