Question

I am a breastfeeding mother and i want to know if it is safe to use G 12144? Is G 12144 safe for nursing mother and child? Does G 12144 extracts into breast milk? Does G 12144 has any long term or short term side effects on infants? Can G 12144 influence milk supply or can G 12144 decrease milk supply in lactating mothers?

G 12144 lactation summary

G 12144 is unsafe in breastfeeding
  • DrLact safety Score for G 12144 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of G 12144 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that G 12144 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using G 12144 .
  • It is recommended to evaluate the advantage of not breastfeeding while using G 12144 Vs not using G 12144 And continue breastfeeding.
  • While using G 12144 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About G 12144 usage in lactation

First generation antihistamine drug which is derived from ethylene diamine with important sedative and antimuscarinic effects. The anticholinergic effect may inhibit lactation. At latest update no published data on excretion into breast milk was found. Drug that is scarcely supported by bibliographical evidence, which is marketed in very few countries from Eastern Europe, Mexico ... Until more published information about this drug regarding breastfeeding appears, it may be preferable the use of a known and safer alternative.

Alternate Drugs for Antihistamines for systemic use. ATC R06A.

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