Is 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone? Is 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone safe for nursing mother and child? Does 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone extracts into breast milk? Does 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone has any long term or short term side effects on infants? Can 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone influence milk supply or can 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone decrease milk supply in lactating mothers?
1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone lactation summary
- DrLact safety Score for 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1-(4-(1,1-Dimethylethyl)phenyl)-4-(4-(diphenylmethoxy)-1-piperidinyl)-1-butanone usage in lactation
Second generation anti-histaminic and piperidine drug with a slightly sedative effect. Second generation anti-histaminic medicines are considered to be safe while breastfeeding. On latest update no relevant data related to breastfeeding was found. Its high protein-binding capacity makes excretion into breast milk unlikely. For long-term treatment a better known drug related to breastfeeding should be preferred.
Alternate Drugs for Antihistamines for systemic use. ATC R06A.
Acrivastine(Low Risk)
Brompheniramine(Low Risk)
Carbinoxamine(Low Risk)
Cetirizine(Safe)
Chlorpheniramine(Low Risk)
Clemastine(Low Risk)
Desloratadine(Safe)
Dexchlorpheniramine(Low Risk)
Dimenhydrinate(Low Risk)
Diphenhydramine(Low Risk)
Fexofenadine(Safe)
Hydroxyzine(Safe)
Loratadine(Safe)
Promethazine(Low Risk)
Pyrilamine(Low Risk)
Thiethylperazine(Unsafe)
Triprolidine(Safe)
Epinastine(Low Risk)
Meclizine(Low Risk)
Ketotifen(Low Risk)
Levocetirizine(Low Risk)
Cyclizine(Low Risk)
Doxylamine(Unsafe)
Cetirizine Hydrochloride(Safe)
Alimemazine(Low Risk)
Astemizole(Unsafe)
Azatadine Maleate(Low Risk)
Bilastine(Low Risk)
Brompheniramine Maleate(Low Risk)
Buclizine-Hcl(Low Risk)
Carbinoxamine Maleate(Low Risk)
Cyproheptadine-Hcl(Low Risk)
Clemastine Fumarate(Low Risk)
Chlorcyclizine(Low Risk)
Chlorphenamine(Low Risk)
Chloropyramine Hydrochloride(Unsafe)
Ebastine(Low Risk)
Ketotifen Fumarate(Low Risk)
Meclozine(Low Risk)
Mepyramine(Low Risk)
Mequitazine(Unsafe)
Mizolastine(Low Risk)
Pizotifen(Low Risk)
Rupatadine Fumarate(Low Risk)
Terfenadine(Low Risk)
Trimeprazine(Low Risk)
Halopyramine Hydrochloride(Unsafe)
Doxylamine Succinate(Unsafe)
Dramamine Ii(Low Risk)
Chlorpheniramine Maleate(Low Risk)
Pizotyline(Low Risk)
Benzhydramine(Low Risk)
Promethazine Hydrochloride(Low Risk)
Pyranisamine(Low Risk)
Kelp(Unsafe)