Is Terfenadina [INN-Spanish] Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use Terfenadina [INN-Spanish]? Is Terfenadina [INN-Spanish] safe for nursing mother and child? Does Terfenadina [INN-Spanish] extracts into breast milk? Does Terfenadina [INN-Spanish] has any long term or short term side effects on infants? Can Terfenadina [INN-Spanish] influence milk supply or can Terfenadina [INN-Spanish] decrease milk supply in lactating mothers?

Terfenadina [INN-Spanish] lactation summary

Terfenadina [INN-Spanish] usage has low risk in breastfeeding

DrLact safety Score for Terfenadina [INN-Spanish] is 3 out of 8 which is considered Low Risk as per our analyses.
A safety Score of 3 indicates that usage of Terfenadina [INN-Spanish] may cause some minor side effects in breastfed baby.
Our study of different scientific research indicates that Terfenadina [INN-Spanish] may cause moderate to no side effects in lactating mother.
Most of scientific studies and research papers declaring usage of Terfenadina [INN-Spanish] low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
While using Terfenadina [INN-Spanish] We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Terfenadina [INN-Spanish] usage in lactation

Second generation anti-histaminic and piperidine drug, with a slightly sedative effect. Irritability has been described. Avoid its use on patients affected of cardiac arrhythmia or along with erythromycin and/or ketoconazole o si el lactante está tomando un macrólido.

Alternate Drugs for Antihistamines for systemic use. ATC R06A.

Acrivastine(Low Risk)

Brompheniramine(Low Risk)

Carbinoxamine(Low Risk)

Cetirizine(Safe)

Chlorpheniramine(Low Risk)

Clemastine(Low Risk)

Desloratadine(Safe)

Dexchlorpheniramine(Low Risk)

Dimenhydrinate(Low Risk)

Diphenhydramine(Low Risk)

Fexofenadine(Safe)

Hydroxyzine(Safe)

Loratadine(Safe)

Promethazine(Low Risk)

Pyrilamine(Low Risk)

Thiethylperazine(Unsafe)

Triprolidine(Safe)

Epinastine(Low Risk)

Meclizine(Low Risk)

Ketotifen(Low Risk)

Levocetirizine(Low Risk)

Cyclizine(Low Risk)

Doxylamine(Unsafe)

Cetirizine Hydrochloride(Safe)

Alimemazine(Low Risk)

Astemizole(Unsafe)

Azatadine Maleate(Low Risk)

Bilastine(Low Risk)

Brompheniramine Maleate(Low Risk)

Buclizine-Hcl(Low Risk)

Carbinoxamine Maleate(Low Risk)

Cyproheptadine-Hcl(Low Risk)

Clemastine Fumarate(Low Risk)

Chlorcyclizine(Low Risk)

Chlorphenamine(Low Risk)

Chloropyramine Hydrochloride(Unsafe)

Ebastine(Low Risk)

Fexofenadine Hydrochloride(Safe)

Ketotifen Fumarate(Low Risk)

Meclozine(Low Risk)

Mepyramine(Low Risk)

Mequitazine(Unsafe)

Mizolastine(Low Risk)

Pizotifen(Low Risk)

Rupatadine Fumarate(Low Risk)

Terfenadine(Low Risk)

Triprolidine Hydrochloride(Safe)

Dimetindene Maleate (systemic use)(Unsafe)

Trimeprazine(Low Risk)

Halopyramine Hydrochloride(Unsafe)

Doxylamine Succinate(Unsafe)

Dramamine Ii(Low Risk)

Chlorpheniramine Maleate(Low Risk)

Pizotyline(Low Risk)

Benzhydramine(Low Risk)

Promethazine Hydrochloride(Low Risk)

Pyranisamine(Low Risk)

Kelp(Unsafe)

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.