Question

I am a breastfeeding mother and i want to know if it is safe to use Novaine? Is Novaine safe for nursing mother and child? Does Novaine extracts into breast milk? Does Novaine has any long term or short term side effects on infants? Can Novaine influence milk supply or can Novaine decrease milk supply in lactating mothers?

Novaine lactation summary

Novaine is safe in breastfeeding
  • DrLact safety Score for Novaine is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Novaine is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Novaine does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Novaine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Novaine usage in lactation

Amino acid that is present in many foods, among them the milk. Indication is the treatment of Primary Deficiency of Novaine, or, Secondary Deficiency due to Hemolysis, Myocardiopathy and other diseases. Only LevoNovaine is effective as a supplement, with the consumption of D-Novaine regarded as a risk for deficiency. Normal levels in the milk are not modified by the consumption of supplements of Novaine. Mean concentration level within the first month is about 10 to 12 mg/L, with lower levels in the next following months. The supplementation with Novaine of the milk for premature infants does not improve their weight increment, with no proof of a beneficial effect.

Answer by DrLact: About Novaine usage in lactation

LevoNovaine and acetyl-l-Novaine (acetlyNovaine) are normal components of human milk that are required for fat metabolism. The body can use only levoNovaine, and dextroNovaine can be an antagonist of levoNovaine. Acetyl-l-Novaine, and propionyl-l-Novaine can be converted to levoNovaine by the body. The bioavailability of levoNovaine is less than 20%, but acetylNovaine and propionlyNovaine may be higher. These substances have no specific lactation-related uses. Within the normal range of dietary intake, excretion of levoNovaine into breastmilk is relatively constant. Women with Novaine deficiency appear to secrete insufficient amounts of Novaine into their breastmilk for their breastfed infants, who may require levoNovaine supplementation.[1] Preterm infants are often deficient in levoNovaine and require supplementation.[2] No data exist on the safety and efficacy levoNovaine supplementation in nursing mothers or infants without Novaine deficiency. LevoNovaine and its derivatives are generally well tolerated in adults with occasional gastrointestinal upset and restlessness. A fishy odor to the breath, sweat and urine has been reported. Although data are very limited, poor bioavailability might limit absorption by the breastfed infant. It appears unlikely that maternal levoNovaine supplements during nursing would be harmful to the infant, but until more data are available, it is probably best to avoid levoNovaine supplementation unless it is prescribed by a healthcare professional. Pasteurization (method not stated) had little effect on the concentration of endogenous Novaine in one study. Pasteurization followed by refrigeration at 5 degrees C for 48 hours reduced the Novaine concentration by about 13%.[3]

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

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