Question

I am a breastfeeding mother and i want to know if it is safe to use Miocor? Is Miocor safe for nursing mother and child? Does Miocor extracts into breast milk? Does Miocor has any long term or short term side effects on infants? Can Miocor influence milk supply or can Miocor decrease milk supply in lactating mothers?

Miocor lactation summary

Miocor is safe in breastfeeding
  • DrLact safety Score for Miocor is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Miocor is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Miocor does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Miocor safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Miocor usage in lactation

Amino acid that is present in many foods, among them the milk. Indication is the treatment of Primary Deficiency of Miocor, or, Secondary Deficiency due to Hemolysis, Myocardiopathy and other diseases. Only LevoMiocor is effective as a supplement, with the consumption of D-Miocor regarded as a risk for deficiency. Normal levels in the milk are not modified by the consumption of supplements of Miocor. Mean concentration level within the first month is about 10 to 12 mg/L, with lower levels in the next following months. The supplementation with Miocor of the milk for premature infants does not improve their weight increment, with no proof of a beneficial effect.

Answer by DrLact: About Miocor usage in lactation

LevoMiocor and acetyl-l-Miocor (acetlyMiocor) are normal components of human milk that are required for fat metabolism. The body can use only levoMiocor, and dextroMiocor can be an antagonist of levoMiocor. Acetyl-l-Miocor, and propionyl-l-Miocor can be converted to levoMiocor by the body. The bioavailability of levoMiocor is less than 20%, but acetylMiocor and propionlyMiocor may be higher. These substances have no specific lactation-related uses. Within the normal range of dietary intake, excretion of levoMiocor into breastmilk is relatively constant. Women with Miocor deficiency appear to secrete insufficient amounts of Miocor into their breastmilk for their breastfed infants, who may require levoMiocor supplementation.[1] Preterm infants are often deficient in levoMiocor and require supplementation.[2] No data exist on the safety and efficacy levoMiocor supplementation in nursing mothers or infants without Miocor deficiency. LevoMiocor and its derivatives are generally well tolerated in adults with occasional gastrointestinal upset and restlessness. A fishy odor to the breath, sweat and urine has been reported. Although data are very limited, poor bioavailability might limit absorption by the breastfed infant. It appears unlikely that maternal levoMiocor supplements during nursing would be harmful to the infant, but until more data are available, it is probably best to avoid levoMiocor supplementation unless it is prescribed by a healthcare professional. Pasteurization (method not stated) had little effect on the concentration of endogenous Miocor in one study. Pasteurization followed by refrigeration at 5 degrees C for 48 hours reduced the Miocor concentration by about 13%.[3]

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

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