Question

I am a breastfeeding mother and i want to know if it is safe to use Excitine? Is Excitine safe for nursing mother and child? Does Excitine extracts into breast milk? Does Excitine has any long term or short term side effects on infants? Can Excitine influence milk supply or can Excitine decrease milk supply in lactating mothers?

Excitine lactation summary

Excitine is safe in breastfeeding
  • DrLact safety Score for Excitine is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Excitine is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Excitine does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Excitine safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Excitine usage in lactation

Amino acid that is present in many foods, among them the milk. Indication is the treatment of Primary Deficiency of Excitine, or, Secondary Deficiency due to Hemolysis, Myocardiopathy and other diseases. Only LevoExcitine is effective as a supplement, with the consumption of D-Excitine regarded as a risk for deficiency. Normal levels in the milk are not modified by the consumption of supplements of Excitine. Mean concentration level within the first month is about 10 to 12 mg/L, with lower levels in the next following months. The supplementation with Excitine of the milk for premature infants does not improve their weight increment, with no proof of a beneficial effect.

Answer by DrLact: About Excitine usage in lactation

LevoExcitine and acetyl-l-Excitine (acetlyExcitine) are normal components of human milk that are required for fat metabolism. The body can use only levoExcitine, and dextroExcitine can be an antagonist of levoExcitine. Acetyl-l-Excitine, and propionyl-l-Excitine can be converted to levoExcitine by the body. The bioavailability of levoExcitine is less than 20%, but acetylExcitine and propionlyExcitine may be higher. These substances have no specific lactation-related uses. Within the normal range of dietary intake, excretion of levoExcitine into breastmilk is relatively constant. Women with Excitine deficiency appear to secrete insufficient amounts of Excitine into their breastmilk for their breastfed infants, who may require levoExcitine supplementation.[1] Preterm infants are often deficient in levoExcitine and require supplementation.[2] No data exist on the safety and efficacy levoExcitine supplementation in nursing mothers or infants without Excitine deficiency. LevoExcitine and its derivatives are generally well tolerated in adults with occasional gastrointestinal upset and restlessness. A fishy odor to the breath, sweat and urine has been reported. Although data are very limited, poor bioavailability might limit absorption by the breastfed infant. It appears unlikely that maternal levoExcitine supplements during nursing would be harmful to the infant, but until more data are available, it is probably best to avoid levoExcitine supplementation unless it is prescribed by a healthcare professional. Pasteurization (method not stated) had little effect on the concentration of endogenous Excitine in one study. Pasteurization followed by refrigeration at 5 degrees C for 48 hours reduced the Excitine concentration by about 13%.[3]

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

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