Question

I am a breastfeeding mother and i want to know if it is safe to use Carnicor? Is Carnicor safe for nursing mother and child? Does Carnicor extracts into breast milk? Does Carnicor has any long term or short term side effects on infants? Can Carnicor influence milk supply or can Carnicor decrease milk supply in lactating mothers?

Carnicor lactation summary

Carnicor is safe in breastfeeding
  • DrLact safety Score for Carnicor is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Carnicor is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Carnicor does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Carnicor safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Carnicor usage in lactation

Amino acid that is present in many foods, among them the milk. Indication is the treatment of Primary Deficiency of Carnicor, or, Secondary Deficiency due to Hemolysis, Myocardiopathy and other diseases. Only LevoCarnicor is effective as a supplement, with the consumption of D-Carnicor regarded as a risk for deficiency. Normal levels in the milk are not modified by the consumption of supplements of Carnicor. Mean concentration level within the first month is about 10 to 12 mg/L, with lower levels in the next following months. The supplementation with Carnicor of the milk for premature infants does not improve their weight increment, with no proof of a beneficial effect.

Answer by DrLact: About Carnicor usage in lactation

LevoCarnicor and acetyl-l-Carnicor (acetlyCarnicor) are normal components of human milk that are required for fat metabolism. The body can use only levoCarnicor, and dextroCarnicor can be an antagonist of levoCarnicor. Acetyl-l-Carnicor, and propionyl-l-Carnicor can be converted to levoCarnicor by the body. The bioavailability of levoCarnicor is less than 20%, but acetylCarnicor and propionlyCarnicor may be higher. These substances have no specific lactation-related uses. Within the normal range of dietary intake, excretion of levoCarnicor into breastmilk is relatively constant. Women with Carnicor deficiency appear to secrete insufficient amounts of Carnicor into their breastmilk for their breastfed infants, who may require levoCarnicor supplementation.[1] Preterm infants are often deficient in levoCarnicor and require supplementation.[2] No data exist on the safety and efficacy levoCarnicor supplementation in nursing mothers or infants without Carnicor deficiency. LevoCarnicor and its derivatives are generally well tolerated in adults with occasional gastrointestinal upset and restlessness. A fishy odor to the breath, sweat and urine has been reported. Although data are very limited, poor bioavailability might limit absorption by the breastfed infant. It appears unlikely that maternal levoCarnicor supplements during nursing would be harmful to the infant, but until more data are available, it is probably best to avoid levoCarnicor supplementation unless it is prescribed by a healthcare professional. Pasteurization (method not stated) had little effect on the concentration of endogenous Carnicor in one study. Pasteurization followed by refrigeration at 5 degrees C for 48 hours reduced the Carnicor concentration by about 13%.[3]

Alternate Drugs for Aminoacids, Enzymes and other Alimentary tract and Metabolism products. ATC A09 & A16

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