I am a breastfeeding mother and i want to know if it is safe to use Serratio peptidase? Is Serratio peptidase safe for nursing mother and child? Does Serratio peptidase extracts into breast milk? Does Serratio peptidase has any long term or short term side effects on infants? Can Serratio peptidase influence milk supply or can Serratio peptidase decrease milk supply in lactating mothers?
- DrLact safety Score for Serratio peptidase is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Serratio peptidase may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Serratio peptidase may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Serratio peptidase low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Serratio peptidase We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
A proteolytic enzyme produced by Serratia spp. It consists of a chain of 470 amino acids of an average molecular weight of 50,600 daltons (Nakahama 1986). It is administered orally to treat inflammation, edema, pain and, as a dietary supplement, to prevent cardiovascular disease. There is no scientific evidence of its efficacy as an analgesic or as a health supplement and there is no data on its long-term safety (Bhagat 2013). Due to its protein nature it would be digested and inactivated in the gastrointestinal tract, not being absorbed as such but in the form of loose amino acids, which is why its oral bioavailability is practically zero. Since the last update we have not found any published data on its excretion in breast milk. Its pharmacokinetic data (very high molecular weight and poor oral bioavailability) make it very unlikely that significant quantities will pass into breast milk. It has been administered orally to treat breast engorgement or inflammation due to milk stasis (Kee 1989), but evidence for its effectiveness is insufficient and comes only from a study by Kee dating from 1989 which had poor results and came from few patients (Mangesi 2016, ABM 2016 y 2009).
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Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.