Question

I am a breastfeeding mother and i want to know if it is safe to use Cidofovir Intralesional? Is Cidofovir Intralesional safe for nursing mother and child? Does Cidofovir Intralesional extracts into breast milk? Does Cidofovir Intralesional has any long term or short term side effects on infants? Can Cidofovir Intralesional influence milk supply or can Cidofovir Intralesional decrease milk supply in lactating mothers?

Cidofovir Intralesional lactation summary

Cidofovir Intralesional usage has low risk in breastfeeding
  • DrLact safety Score for Cidofovir Intralesional is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Cidofovir Intralesional may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Cidofovir Intralesional may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Cidofovir Intralesional low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Cidofovir Intralesional We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Cidofovir Intralesional usage in lactation

Used for treatment of CMV retinitis in HIV patients. Toxic effect on kidney function Topically used for intralesional treatment of recurrent laringeal papillomatosis caused by the Human Papilloma Virus, even in infants and children, without side effects. Serum level after intralesional injection varies from 0 to 0.4 mg/L, which is fifty times lower than after intravenous administration. Excretion into breast milk is unknown but absorption by the intestine should be very poor.
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