Question

I am a breastfeeding mother and i want to know if it is safe to use NCI-C04580? Is NCI-C04580 safe for nursing mother and child? Does NCI-C04580 extracts into breast milk? Does NCI-C04580 has any long term or short term side effects on infants? Can NCI-C04580 influence milk supply or can NCI-C04580 decrease milk supply in lactating mothers?

NCI-C04580 lactation summary

NCI-C04580 is unsafe in breastfeeding
  • DrLact safety Score for NCI-C04580 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of NCI-C04580 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that NCI-C04580 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using NCI-C04580 .
  • It is recommended to evaluate the advantage of not breastfeeding while using NCI-C04580 Vs not using NCI-C04580 And continue breastfeeding.
  • While using NCI-C04580 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NCI-C04580 usage in lactation

It is a halogenated hydrocarbon product. A fluid industrially used in dry cleaning, oil and stain removal. Appropriate ventilation is required to keep TLV-TWA less than 50 ppm (339mg/m3).It is irritant to skin and mucous surfaces, and a CNS depressant substance. Accidentally occurring exposure is very dangerous to the mother (TLV-STEL must be less than 200 ppm=1357mg/m3). In case of such exposure, the mother should stop nursing the baby for the next 15 days (a case of one infant who developed severe jaundice after having been nursed by a recent exposed women). It is worth to test levels on breast milk.

Alternate Drugs for Contaminant, Environmental Pollutant

Hydroquinone(Low Risk)
Aflatoxin(Low Risk)
Aniline(Unsafe)
Bromum(Low Risk)
Cadmium(Low Risk)
Cobalt(Safe)
DDT(Low Risk)
Dieldrin(Low Risk)
Formaldehyde(Unsafe)
White-Spirit(Unsafe)
Mercury(Low Risk)
Nitrate(Low Risk)
Lead(Unsafe)
Aminobenzene(Unsafe)
Phenylamine(Unsafe)
Hydroquinol(Low Risk)
Methanal(Unsafe)
1,4-Benzenediol(Low Risk)
Quinol(Low Risk)
Formalin(Unsafe)
Formol(Unsafe)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.