Is UNII-YG0E19592I Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-YG0E19592I? Is UNII-YG0E19592I safe for nursing mother and child? Does UNII-YG0E19592I extracts into breast milk? Does UNII-YG0E19592I has any long term or short term side effects on infants? Can UNII-YG0E19592I influence milk supply or can UNII-YG0E19592I decrease milk supply in lactating mothers?
UNII-YG0E19592I lactation summary
- DrLact safety Score for UNII-YG0E19592I is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-YG0E19592I may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-YG0E19592I may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-YG0E19592I low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-YG0E19592I We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-YG0E19592I usage in lactation
Drug with similar efficacy as other antidepressants with tricyclic and selective inhibitors of serotonin reuptake characteristics.Risk of abuse and dependence with addiction, which is a reason not to be authorized in many countries.Neonatal Abstinence Syndrome has been published after abusing doses (more than 100 times higher than usual) of Tianeptine during pregnancy (Bence 2016). At latest update no published data on excretion into breast milk were found. Its high plasma protein-binding capacity makes it unlikely the passage of drug into breast milk. It may, like other antidepressants, increase Prolactin levels in the plasma. Until more published data regarding breastfeeding is available, the use of a known and safer alternative drug should be preferred, especially during the neonatal period and/or in case of premature infant.
Alternate Drugs for Antidepressants, other. ATC N06AX
Trazodone(Safe)
Mirtazapine(Safe)
Venlafaxine(Safe)
Duloxetine(Safe)
Desvenlafaxine(Safe)
Milnacipran(Unsafe)
Levomilnacipran(Unsafe)
Vortioxetine(Low Risk)
Agomelatine(Low Risk)
Mianserin-Hcl(Low Risk)
Nefazodone-Hcl(Dangerous)
Oxytriptan(Low Risk)
Tianeptine Sodium(Low Risk)
Viloxazine-Hcl(Unsafe)
Vortioxetine Hydrobromide(Low Risk)
Duloxetine Hydrochloride(Safe)
Mepirzepine(Safe)
Midalcipran(Unsafe)
Desvenlafaxine Succinate(Safe)
Trazodone Hydrochloride(Safe)