Is 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate? Is 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate safe for nursing mother and child? Does 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate extracts into breast milk? Does 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate has any long term or short term side effects on infants? Can 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate influence milk supply or can 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate decrease milk supply in lactating mothers?
1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate lactation summary
- DrLact safety Score for 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 1-Piperazinecarboxamide, N,N-diethyl-4-methyl-, 2-hydroxy-1,2,3-propanetricarboxylate usage in lactation
Used in the treatment of filaria, loa, mansonella and toxocara infection. Not longer recommended for onchocerciasis. Dosage for children is available. Periodic treatment strategies for entire populations have been undertaken (not recommended for newborns). Diethylcarbamazine enriched salt has been used. Check-up for untoward effects related to the drug itself which are usually mild and parasite killing dependent. Not commercially available in Spain.
Alternate Drugs for Anthelmintic
Mebendazole(Safe)
Praziquantel(Safe)
Ivermectin(Safe)
Albendazole(Safe)
Pyrantel(Safe)
Pyrantel Embonate(Safe)
Diethylcarbamazine Citrate(Low Risk)
Flubendazole(Safe)
Levamisole(Low Risk)
Niclosamide(Safe)
Oxamniquine(Safe)
Piperazine(Low Risk)
Thiabendazole(Low Risk)
Dispermine(Low Risk)
Piperazidine(Low Risk)
Pyrantel Pamoate(Safe)