Question

I am a breastfeeding mother and i want to know if it is safe to use (2-Hydroxyethyl)trimethylammonium chloride succinate? Is (2-Hydroxyethyl)trimethylammonium chloride succinate safe for nursing mother and child? Does (2-Hydroxyethyl)trimethylammonium chloride succinate extracts into breast milk? Does (2-Hydroxyethyl)trimethylammonium chloride succinate has any long term or short term side effects on infants? Can (2-Hydroxyethyl)trimethylammonium chloride succinate influence milk supply or can (2-Hydroxyethyl)trimethylammonium chloride succinate decrease milk supply in lactating mothers?

(2-Hydroxyethyl)trimethylammonium chloride succinate lactation summary

(2-Hydroxyethyl)trimethylammonium chloride succinate is safe in breastfeeding
  • DrLact safety Score for (2-Hydroxyethyl)trimethylammonium chloride succinate is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of (2-Hydroxyethyl)trimethylammonium chloride succinate is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that (2-Hydroxyethyl)trimethylammonium chloride succinate does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of (2-Hydroxyethyl)trimethylammonium chloride succinate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About (2-Hydroxyethyl)trimethylammonium chloride succinate usage in lactation

Muscle-relaxant agent with a peripheric depolarizing action that is used for rapid endotracheal intubation procedures, which also has a transient effect. At latest update, no relevant published data concerning excretion into breast milk were found. Because of a very rapid half-life elimination period (less than 1 minute), a significant excretion into breast milk is unlikely. Also, a low oral bioavailability renders the pass of this agent to the infant's plasma, highly unlikely. Succinylcholine should not prevent a mother from breast feeding her baby shortly after recovering from an anesthesia if she is in a good condition. List of Medicines (WHO-2002): compatible with Breastfeeding.

Alternate Drugs for Muscle relaxants. ATC M03

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