Question

I am a breastfeeding mother and i want to know if it is safe to use DS 103-282? Is DS 103-282 safe for nursing mother and child? Does DS 103-282 extracts into breast milk? Does DS 103-282 has any long term or short term side effects on infants? Can DS 103-282 influence milk supply or can DS 103-282 decrease milk supply in lactating mothers?

DS 103-282 lactation summary

DS 103-282 is unsafe in breastfeeding
  • DrLact safety Score for DS 103-282 is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of DS 103-282 may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that DS 103-282 may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using DS 103-282 .
  • It is recommended to evaluate the advantage of not breastfeeding while using DS 103-282 Vs not using DS 103-282 And continue breastfeeding.
  • While using DS 103-282 Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About DS 103-282 usage in lactation

Centrally acting muscle relaxant. Since the last update we have not found published data on its excretion in breast milk. Its pharmacokinetic data: low molecular weight, high liposolubility (Acorda 2006), makes it probable that it could pass to milk in potentially significant quantities. During breastfeeding, it seems prudent to avoid it (Hutchinson 2013) or to use it very sporadically and limited to sufficient minimum doses, monitoring for possible sedation of the infant, especially during the first 3 months of life.

Alternate Drugs for Muscle relaxants. ATC M03

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