Question

I am a breastfeeding mother and i want to know if it is safe to use 5-Chlorbenzoxazolin-2-on? Is 5-Chlorbenzoxazolin-2-on safe for nursing mother and child? Does 5-Chlorbenzoxazolin-2-on extracts into breast milk? Does 5-Chlorbenzoxazolin-2-on has any long term or short term side effects on infants? Can 5-Chlorbenzoxazolin-2-on influence milk supply or can 5-Chlorbenzoxazolin-2-on decrease milk supply in lactating mothers?

5-Chlorbenzoxazolin-2-on lactation summary

5-Chlorbenzoxazolin-2-on is unsafe in breastfeeding
  • DrLact safety Score for 5-Chlorbenzoxazolin-2-on is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 5-Chlorbenzoxazolin-2-on may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 5-Chlorbenzoxazolin-2-on may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 5-Chlorbenzoxazolin-2-on .
  • It is recommended to evaluate the advantage of not breastfeeding while using 5-Chlorbenzoxazolin-2-on Vs not using 5-Chlorbenzoxazolin-2-on And continue breastfeeding.
  • While using 5-Chlorbenzoxazolin-2-on Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-Chlorbenzoxazolin-2-on usage in lactation

Centrally-acting muscle relaxant with sedative properties. Administered orally.It has pharmacokinetics with rapid absorption and elimination (PDR 2017, Prompila 2007, Desiraju 1983). Since the last update we have not found published data about its excretion in breast milk. Its pharmacokinetic data (low molecular weight, low protein binding, small volume of distribution) make its likely that it could pass into breast milk in quantities that could be significant. If you have to use it during breastfeeding, you should monitor sedative effects in the baby. To minimize exposure, medication can be taken just after a feed and waiting 3-4 hours before breastfeeding again.

Alternate Drugs for Muscle relaxants. ATC M03

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