Question

I am a breastfeeding mother and i want to know if it is safe to use 5-Chlorobenzoxazolone? Is 5-Chlorobenzoxazolone safe for nursing mother and child? Does 5-Chlorobenzoxazolone extracts into breast milk? Does 5-Chlorobenzoxazolone has any long term or short term side effects on infants? Can 5-Chlorobenzoxazolone influence milk supply or can 5-Chlorobenzoxazolone decrease milk supply in lactating mothers?

5-Chlorobenzoxazolone lactation summary

5-Chlorobenzoxazolone is unsafe in breastfeeding
  • DrLact safety Score for 5-Chlorobenzoxazolone is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 5-Chlorobenzoxazolone may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 5-Chlorobenzoxazolone may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 5-Chlorobenzoxazolone .
  • It is recommended to evaluate the advantage of not breastfeeding while using 5-Chlorobenzoxazolone Vs not using 5-Chlorobenzoxazolone And continue breastfeeding.
  • While using 5-Chlorobenzoxazolone Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-Chlorobenzoxazolone usage in lactation

Centrally-acting muscle relaxant with sedative properties. Administered orally.It has pharmacokinetics with rapid absorption and elimination (PDR 2017, Prompila 2007, Desiraju 1983). Since the last update we have not found published data about its excretion in breast milk. Its pharmacokinetic data (low molecular weight, low protein binding, small volume of distribution) make its likely that it could pass into breast milk in quantities that could be significant. If you have to use it during breastfeeding, you should monitor sedative effects in the baby. To minimize exposure, medication can be taken just after a feed and waiting 3-4 hours before breastfeeding again.

Alternate Drugs for Muscle relaxants. ATC M03

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