Question

I am a breastfeeding mother and i want to know if it is safe to use EINECS 203-414-1? Is EINECS 203-414-1 safe for nursing mother and child? Does EINECS 203-414-1 extracts into breast milk? Does EINECS 203-414-1 has any long term or short term side effects on infants? Can EINECS 203-414-1 influence milk supply or can EINECS 203-414-1 decrease milk supply in lactating mothers?

EINECS 203-414-1 lactation summary

EINECS 203-414-1 usage has low risk in breastfeeding
  • DrLact safety Score for EINECS 203-414-1 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of EINECS 203-414-1 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that EINECS 203-414-1 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of EINECS 203-414-1 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using EINECS 203-414-1 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About EINECS 203-414-1 usage in lactation

It is locally used together with photo-dynamic therapy (especial blue light) as a treatment of Actinic Dermatitis and Basocelular Carcinoma. At latest update, relevant information on excretion into breast milk was not found. Absorption through the skin is very low (0.26 % of administered dose), hence, a low or non-significant level in the mother's plasma should be expected. In case that a complete elimination of drug would be desired, a time period equivalent to ten times a half-life (Mean time) should be observed after drug administration to resume breastfeeding. In this case it would be equal to 8-10 hours. In the mean while, pump-and-dump regularly to maintain milk production. Do not apply it on the breast or cleanse it thoroughly to keep the baby from swallowing.

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