Is alpha-Asparaginase Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use alpha-Asparaginase? Is alpha-Asparaginase safe for nursing mother and child? Does alpha-Asparaginase extracts into breast milk? Does alpha-Asparaginase has any long term or short term side effects on infants? Can alpha-Asparaginase influence milk supply or can alpha-Asparaginase decrease milk supply in lactating mothers?
alpha-Asparaginase lactation summary
- DrLact safety Score for alpha-Asparaginase is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of alpha-Asparaginase may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that alpha-Asparaginase may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using alpha-Asparaginase .
- Usage of alpha-Asparaginase is in contradiction to breastfeeding hence if it is must to use alpha-Asparaginase and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About alpha-Asparaginase usage in lactation
Drug is cleared from the body in 5 half-lives elimination period. Resuming breastfeeding is likely safe after 10 pump-and-dump days period. Pumping is important to keep milk production.
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