Is 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin? Is 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin safe for nursing mother and child? Does 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin extracts into breast milk? Does 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin has any long term or short term side effects on infants? Can 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin influence milk supply or can 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin decrease milk supply in lactating mothers?
4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin lactation summary
- DrLact safety Score for 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin .
- Usage of 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin is in contradiction to breastfeeding hence if it is must to use 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About 4-Amino-1-arabinofuranosyl-2-oxo-1,2-dihydropyrimidin usage in lactation
Drug is cleared from the body in 8 elimination half-lives. Resuming breastfeeding is likely safe after 24 hours of pumping-and-dumping.
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