Is gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid? Is gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid safe for nursing mother and child? Does gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid extracts into breast milk? Does gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid has any long term or short term side effects on infants? Can gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid influence milk supply or can gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid decrease milk supply in lactating mothers?
gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid lactation summary
- DrLact safety Score for gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid .
- Usage of gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid is in contradiction to breastfeeding hence if it is must to use gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About gamma-(p-bis(2-chloroethyl)aminophenyl)butyricacid usage in lactation
Drug is cleared from the body in 12 elimination half-lives. Resuming breastfeeding is likely safe after 24 hours of pumping-and-dumping.
Alternate Drugs for Antineoplastic agents. ATC L01
Busulfan(Dangerous)
Cisplatin(Unsafe)
Cyclophosphamide(Dangerous)
Doxorubicin(Dangerous)
Etoposide(Dangerous)
Hydroxyurea(Low Risk)
Mercaptopurine(Safe)
Mitoxantrone(Dangerous)
Vincristine(Dangerous)
Methotrexate(Low Risk)
Imatinib(Unsafe)
Trastuzumab(Unsafe)
Bevacizumab(Low Risk)
Rituximab(Low Risk)
Alemtuzumab(Low Risk)
Fluorouracil(Dangerous)
Paclitaxel(Dangerous)
Carboplatin(Dangerous)
Cetuximab(Unsafe)
Brentuximab Vedotin(Low Risk)
Ipilimumab(Unsafe)
Everolimus(Unsafe)
Thioguanine(Dangerous)
Dacarbazine(Dangerous)
Vinorelbine(Dangerous)
Bleomycin(Dangerous)
Vinblastine(Dangerous)
Nivolumab(Unsafe)
Nilotinib(Unsafe)
Dasatinib(Unsafe)
Cladribine(Dangerous)
Erlotinib(Unsafe)
Pazopanib(Unsafe)
Capecitabine(Dangerous)
Docetaxel(Dangerous)
Carmustine(Dangerous)
Exemestane(Dangerous)
Gemcitabine(Dangerous)
Dactinomycin(Dangerous)
Epirubucin(Dangerous)
Fluorouracil Topical Solution(Low Risk)
Idarubicin-Hcl(Dangerous)
Ifosfamide(Dangerous)
Melphalan(Dangerous)
Mitomycin(Dangerous)
Oxaliplatin(Dangerous)
Pentostatin(Dangerous)
Procarbazine(Dangerous)
Teniposide(Dangerous)
Thiotepa(Dangerous)
Tretinoin Oral(Dangerous)
Vinorelbine Tartrate(Dangerous)
Imatinib Mesilate(Unsafe)
Altretamine(Dangerous)
Aminoglutethimide(Dangerous)
5-Aminolevulinic Acid(Low Risk)
Hydroxycarbamide(Low Risk)
Anastrozole(Dangerous)
Arsenic-Trioxide(Dangerous)
Asparaginase(Dangerous)
Bexarotene(Dangerous)
Cytarabine(Dangerous)
Chlorambucil(Dangerous)
Chlormethine(Dangerous)
Daunorubicin(Dangerous)
Rubidomycin(Dangerous)
Amethopterin(Low Risk)
Vincaleukoblastine(Dangerous)
Doxorubicin Hydrochloride(Dangerous)
Vlb(Dangerous)
Mechlorethamine(Dangerous)
Platinum Diamminodichloride(Unsafe)
4-Amino-10-methylfolic Acid(Low Risk)
5-ALA(Low Risk)
5-Fu(Dangerous)
6-Mercaptopurine(Safe)
6-Thiohypoxanthine(Safe)
6-Thioxopurine(Safe)
MTX(Low Risk)
Cytosine Arabinoside(Dangerous)
Daunomycin(Dangerous)
Actinomycin D(Dangerous)
Deoxycoformycin(Dangerous)