Is Disodium etidronate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Disodium etidronate? Is Disodium etidronate safe for nursing mother and child? Does Disodium etidronate extracts into breast milk? Does Disodium etidronate has any long term or short term side effects on infants? Can Disodium etidronate influence milk supply or can Disodium etidronate decrease milk supply in lactating mothers?
Disodium etidronate lactation summary
- DrLact safety Score for Disodium etidronate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Disodium etidronate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Disodium etidronate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Disodium etidronate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Disodium etidronate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Disodium etidronate usage in lactation
It is composed by bisphosphonates. Most bisphosphonates are acidic compounds that achieve low plasma concentration. Both features make it unlikely excretion into the milk in clinically significant amount. Intestinal absorption of bisphosphonates is very low even during fasting and is considered negligible in the presence of milk due to formation with the calcium of non absorbable compounds. A latest update no published data were found on excretion in the breast milk. Until more data about this drug regarding breastfeeding is available, safer known alternatives (pamidronate) should be of choice, especially in the neonatal period and in case of prematurity.
Alternate Drugs for Drugs for Bone Diseases and Mineralization. M05
Alendronate(Low Risk)
Ibandronate(Low Risk)
Risedronate(Low Risk)
Denosumab(Low Risk)
Alendronate Sodium(Low Risk)
Pamidronate Disodium(Safe)
Etidronate Disodium(Low Risk)
Risedronate Sodium(Low Risk)
Tiludronate Sodium(Low Risk)
Zoledronate Disodium(Low Risk)
Ibandronate Sodium(Low Risk)