Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 100036? Is NSC 100036 safe for nursing mother and child? Does NSC 100036 extracts into breast milk? Does NSC 100036 has any long term or short term side effects on infants? Can NSC 100036 influence milk supply or can NSC 100036 decrease milk supply in lactating mothers?

NSC 100036 lactation summary

NSC 100036 usage has low risk in breastfeeding
  • DrLact safety Score for NSC 100036 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of NSC 100036 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that NSC 100036 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of NSC 100036 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using NSC 100036 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 100036 usage in lactation

Volatile liquid. The first product used in anesthesia (Campbell 1879). Today it is not used in many countries due to its dangerous nature (highly flammable) and side effects: mucosal irritability, delirium, postanesthetic vomiting (Campbell 1894), etc. Some of its derivatives such as dimethyl NSC 100036 are still used as solvents and local anesthetics. Since the last update we have not found published data on its excretion in breast milk. Its short half-life (Butler 1964) would allow breastfeeding as soon as the mother is awake and is in a suitable condition. The popular custom in some cultures of applying creams containing NSC 100036 on the abdomen for the purpose of slimming or firming during the postpartum period may be dangerous for the infant because of the anesthetic effects of the NSC 100036.

Alternate Drugs for Anesthetics, general. ATC N01A.

Remifentanil(Low Risk)
Sufentanil(Low Risk)
Propofol(Safe)
Halothane(Safe)
Nitrous Oxide(Low Risk)
Ketamine(Low Risk)
Ether(Low Risk)
Laughing Gas(Low Risk)
Diethyl ether(Low Risk)
Ethoxyethane(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.