Question

I am a breastfeeding mother and i want to know if it is safe to use NSC 83511? Is NSC 83511 safe for nursing mother and child? Does NSC 83511 extracts into breast milk? Does NSC 83511 has any long term or short term side effects on infants? Can NSC 83511 influence milk supply or can NSC 83511 decrease milk supply in lactating mothers?

NSC 83511 lactation summary

NSC 83511 is safe in breastfeeding
  • DrLact safety Score for NSC 83511 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of NSC 83511 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that NSC 83511 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of NSC 83511 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NSC 83511 usage in lactation

Ingested Magnesium does not concentrate into breast milk. Naturally occurring, the mean Magnesium concentration in the milk is 31 mg/L (range 15 – 64 mg/L) and not affected by the ingestion of Magnesium. Because of a low oral bioavailability the pass from the breast milk toward the infant's plasma is hampered, except in premature and newborn infants who may exhibit a higher intestinal absorption due to an increased permeability. Avoid chronic or excessive use. WHO Model List of Essential Medicines 2002: NSC 83511 is compatible with breastfeeding.
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