Is trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine? Is trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine safe for nursing mother and child? Does trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine extracts into breast milk? Does trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine has any long term or short term side effects on infants? Can trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine influence milk supply or can trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine decrease milk supply in lactating mothers?
trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine lactation summary
- DrLact safety Score for trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About trans-3,4-Dimethyl-4-(3-hydroxyphenyl) piperidine usage in lactation
It is a μ-opioid receptor antagonist that accelerates intestinal transit. Prescribed after intestinal surgery procedures. Since oral absorption and plasma levels are very low secretion into breast milk is thought to be minimal.
Alternate Drugs for Laxatives. ATC A06
Bisacodyl(Safe)
Cascara Sagrada(Low Risk)
Docusate(Safe)
Senna(Safe)
Aloe(Low Risk)
Castor(Unsafe)
Sodium Picosulfate(Safe)
Linaclotide(Safe)
Lactulose(Safe)
Alvimopan(Low Risk)
Carabaña Water(Low Risk)
Casanthranol(Low Risk)
Phenolphthalein(Dangerous)
Glycerin(Low Risk)
Guar Gum(Safe)
Isphagula(Safe)
Castor Oil(Unsafe)
Methylcellulose(Safe)
Sodium Sulfate(Safe)
Sodium Laurilsulfate(Safe)
Glycerol(Low Risk)
Docusate Calcium(Safe)
Docusate Sodium(Safe)