Is NCI-C55798 Safe in Breastfeeding

Question

I am a breastfeeding mother and i want to know if it is safe to use NCI-C55798? Is NCI-C55798 safe for nursing mother and child? Does NCI-C55798 extracts into breast milk? Does NCI-C55798 has any long term or short term side effects on infants? Can NCI-C55798 influence milk supply or can NCI-C55798 decrease milk supply in lactating mothers?

NCI-C55798 lactation summary

NCI-C55798 is dangerous in breastfeeding

DrLact safety Score for NCI-C55798 is 7 out of 8 which is considered Dangerous as per our analyses.
A safety Score of 7 indicates that usage of NCI-C55798 may cause toxic or severe side effects in breastfed baby.
Our study of different scientific research indicates that NCI-C55798 may cause moderate to high side effects or may affect milk supply in lactating mother.
Our suggestion is to use safer alternate options rather than using NCI-C55798 .
Usage of NCI-C55798 is in contradiction to breastfeeding hence if it is must to use NCI-C55798 and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About NCI-C55798 usage in lactation

Stimulants, cathartic laxative drug which is irritant to intestinal mucosa. Risk of diarrhea among toddlers. Safer laxative drugs are those bulk-inducing, osmotic, emollient or stool softener agents. A balanced and fiber-rich diet, high fluid intake and physical exercise are of paramount importance to fight constipation. There are evidence of carcinogenicity from studies in experimental animals.