Is NCI-C50395 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use NCI-C50395? Is NCI-C50395 safe for nursing mother and child? Does NCI-C50395 extracts into breast milk? Does NCI-C50395 has any long term or short term side effects on infants? Can NCI-C50395 influence milk supply or can NCI-C50395 decrease milk supply in lactating mothers?
NCI-C50395 lactation summary
- DrLact safety Score for NCI-C50395 is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of NCI-C50395 is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that NCI-C50395 does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of NCI-C50395 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About NCI-C50395 usage in lactation
Natural polysaccharide obtained from the seeds of the leguminous plant cyamopsis tetragonolobus. Indigestible and unabsorbable, it reduces the intestinal absorption of nutrients (carbohydrates, fats). It has satiating properties and is a mild laxative. It is a thickener and gelling agent used in the food and pharmaceutical industries. Devoid of toxicity. Since the last update we have not found published data on its excretion in breast milk. Its pharmacokinetic data (very high molecular weight and lack of intestinal absorption) make it very unlikely that significant amounts would pass into breast milk, or be absorbed by the infant. Diet, exercise, and breastfeeding improve blood sugar levels.
Alternate Drugs for Laxatives. ATC A06
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Cascara Sagrada(Low Risk)
Docusate(Safe)
Senna(Safe)
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Castor(Unsafe)
Sodium Picosulfate(Safe)
Linaclotide(Safe)
Lactulose(Safe)
Alvimopan(Low Risk)
Carabaña Water(Low Risk)
Casanthranol(Low Risk)
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Glycerin(Low Risk)
Guar Gum(Safe)
Isphagula(Safe)
Castor Oil(Unsafe)
Methylcellulose(Safe)
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Glycerol(Low Risk)
Docusate Calcium(Safe)
Docusate Sodium(Safe)