Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-458VC51857? Is UNII-458VC51857 safe for nursing mother and child? Does UNII-458VC51857 extracts into breast milk? Does UNII-458VC51857 has any long term or short term side effects on infants? Can UNII-458VC51857 influence milk supply or can UNII-458VC51857 decrease milk supply in lactating mothers?

UNII-458VC51857 lactation summary

UNII-458VC51857 usage has low risk in breastfeeding
  • DrLact safety Score for UNII-458VC51857 is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-458VC51857 may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-458VC51857 may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-458VC51857 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-458VC51857 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-458VC51857 usage in lactation

Pro-kinetic and selective agonist drug of 5-HT4 receptor of serotonin that may enhance bowel and colon motility. Indicated for treatment of irritable colon syndrome with predominant constipation. It may be a cause of diarrhea and flatulence. Not commercially available in Spain

Alternate Drugs for Other Intestinal agents.

Alosetron(Low Risk)
Tegaserod(Low Risk)

Synonyms of UNII-458VC51857

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