Question

I am a breastfeeding mother and i want to know if it is safe to use Immunoglobulin G1, anti-(human interleukin 6 receptor)? Is Immunoglobulin G1, anti-(human interleukin 6 receptor) safe for nursing mother and child? Does Immunoglobulin G1, anti-(human interleukin 6 receptor) extracts into breast milk? Does Immunoglobulin G1, anti-(human interleukin 6 receptor) has any long term or short term side effects on infants? Can Immunoglobulin G1, anti-(human interleukin 6 receptor) influence milk supply or can Immunoglobulin G1, anti-(human interleukin 6 receptor) decrease milk supply in lactating mothers?

Immunoglobulin G1, anti-(human interleukin 6 receptor) lactation summary

Immunoglobulin G1, anti-(human interleukin 6 receptor) usage has low risk in breastfeeding
  • DrLact safety Score for Immunoglobulin G1, anti-(human interleukin 6 receptor) is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of Immunoglobulin G1, anti-(human interleukin 6 receptor) may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that Immunoglobulin G1, anti-(human interleukin 6 receptor) may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of Immunoglobulin G1, anti-(human interleukin 6 receptor) low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using Immunoglobulin G1, anti-(human interleukin 6 receptor) We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Immunoglobulin G1, anti-(human interleukin 6 receptor) usage in lactation

Monoclonal antibody that inhibits the Interleukin-6 receptor (IL-6r) which is used for treatment of Rheumatoid Arthritis, some types of Juvenile Arthritis and Castleman's disease. At latest update no published data on excretion into breast milk were found. Its high molecular weight makes that excretion into breast milk be very unlikely. Because of a low oral bioavailability it is thought that amount absorbed to the infant's plasma from ingested breast milk would be nil or minimal, except in the immediate newborn period or in case of prematurity who may show an increased intestinal absorption. Until more data on this drug is available, it would be preferred other options that are known to be safer, specially during the neonatal period and prematurity.
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.