Is (R)-N-2-Propynyl-1-indanamine Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use (R)-N-2-Propynyl-1-indanamine? Is (R)-N-2-Propynyl-1-indanamine safe for nursing mother and child? Does (R)-N-2-Propynyl-1-indanamine extracts into breast milk? Does (R)-N-2-Propynyl-1-indanamine has any long term or short term side effects on infants? Can (R)-N-2-Propynyl-1-indanamine influence milk supply or can (R)-N-2-Propynyl-1-indanamine decrease milk supply in lactating mothers?
(R)-N-2-Propynyl-1-indanamine lactation summary
- DrLact safety Score for (R)-N-2-Propynyl-1-indanamine is 7 out of 8 which is considered Dangerous as per our analyses.
- A safety Score of 7 indicates that usage of (R)-N-2-Propynyl-1-indanamine may cause toxic or severe side effects in breastfed baby.
- Our study of different scientific research indicates that (R)-N-2-Propynyl-1-indanamine may cause moderate to high side effects or may affect milk supply in lactating mother.
- Our suggestion is to use safer alternate options rather than using (R)-N-2-Propynyl-1-indanamine .
- Usage of (R)-N-2-Propynyl-1-indanamine is in contradiction to breastfeeding hence if it is must to use (R)-N-2-Propynyl-1-indanamine and there is no better alternative available then breastfeeding shall be stopped permanently or temporarily.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About (R)-N-2-Propynyl-1-indanamine usage in lactation
It a selective MAO-B inhibitor that increases Dopamine serum concentration and inhibits Prolactin secretion and hence decreasing the breast milk production.
Alternate Drugs for Anti-parkinson drugs: Anticholinergics & Dopaminergic agents. ATC N04
Amantadine(Low Risk)
Bromocriptine(Unsafe)
Levodopa(Unsafe)
Ropinirole(Unsafe)
Pramipexole(Unsafe)
Amantadine Hydrochloride(Low Risk)
Apomorphine-Hydrochloride(Low Risk)
Biperiden(Unsafe)
Bromocriptine Mesilate(Unsafe)
Carbidopa(Low Risk)
Orphenadrine(Low Risk)
Procyclidine(Unsafe)
Rasagiline(Dangerous)
Ropinirole Hydrochloride(Unsafe)
Orphenadrine Citrate(Low Risk)
L-Dopa(Unsafe)