Question

I am a breastfeeding mother and i want to know if it is safe to use Propyl 3,5-diiodo-4-pyridone-N-acetate? Is Propyl 3,5-diiodo-4-pyridone-N-acetate safe for nursing mother and child? Does Propyl 3,5-diiodo-4-pyridone-N-acetate extracts into breast milk? Does Propyl 3,5-diiodo-4-pyridone-N-acetate has any long term or short term side effects on infants? Can Propyl 3,5-diiodo-4-pyridone-N-acetate influence milk supply or can Propyl 3,5-diiodo-4-pyridone-N-acetate decrease milk supply in lactating mothers?

Propyl 3,5-diiodo-4-pyridone-N-acetate lactation summary

Propyl 3,5-diiodo-4-pyridone-N-acetate is safe in breastfeeding
  • DrLact safety Score for Propyl 3,5-diiodo-4-pyridone-N-acetate is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of Propyl 3,5-diiodo-4-pyridone-N-acetate is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that Propyl 3,5-diiodo-4-pyridone-N-acetate does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of Propyl 3,5-diiodo-4-pyridone-N-acetate safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About Propyl 3,5-diiodo-4-pyridone-N-acetate usage in lactation

X-ray contrast medium with a content of 57% of iodine, used for performance of a Bronchography by bronchial instillation of contrast media. At latest update no published data were found on excretion into breast milk. The various iodinated contrast media for imaging examinations (X-rays, CT scans) are considered compatible with breastfeeding since they are rapidly eliminated with little or no release of iodine, not metabolized and virtually not absorbed when taken by mouth. They are structurally very similar to each other and one of them is their data no or minimal excretion in milk. Given the low lipid solubility of the iodinated contrast, less than 1% of the dose administered to the mother just passing milk.Due to their low oral bioavailability, intestinal absorption is less than 1% of the dose that he may take the infant.The maximum dose just getting the baby is less than 0.01% of the maternal dose, which represents less than 1% of the dose administered to a nursing practice that is a radiological contrast examination. Most radiology scientific societies agree that after a radiological iodinated contrast examination is not necessary to wait any time to resume nursing. WHO List of Essential Medicines 2002 states it is compatible with breastfeeding.
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