Is Amgen Megakaryopoiesis protein 531 Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Amgen Megakaryopoiesis protein 531? Is Amgen Megakaryopoiesis protein 531 safe for nursing mother and child? Does Amgen Megakaryopoiesis protein 531 extracts into breast milk? Does Amgen Megakaryopoiesis protein 531 has any long term or short term side effects on infants? Can Amgen Megakaryopoiesis protein 531 influence milk supply or can Amgen Megakaryopoiesis protein 531 decrease milk supply in lactating mothers?
Amgen Megakaryopoiesis protein 531 lactation summary
- DrLact safety Score for Amgen Megakaryopoiesis protein 531 is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Amgen Megakaryopoiesis protein 531 may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Amgen Megakaryopoiesis protein 531 may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Amgen Megakaryopoiesis protein 531 low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Amgen Megakaryopoiesis protein 531 We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Amgen Megakaryopoiesis protein 531 usage in lactation
An Fc-peptide fusion protein that acts as an agonist in the thrombopoietin receptor stimulating platelet production.Indicated in the treatment of chronic immune thrombocytopenic purpura (ITP) when resistant to other treatments (corticoids, immunoglobulins).Administered subcutaneously once a week. Since the last update, we have not found published data on its excretion in breast milk. Its very high molecular weight makes it very unlikely that it will transfer to milk in significant quantities. Due to its protein nature it is inactivated in the gastrointestinal tract, not being absorbed, so that its oral bioavailability is practically nil, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.
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