Is UNII-GN5XU2DXKV Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use UNII-GN5XU2DXKV? Is UNII-GN5XU2DXKV safe for nursing mother and child? Does UNII-GN5XU2DXKV extracts into breast milk? Does UNII-GN5XU2DXKV has any long term or short term side effects on infants? Can UNII-GN5XU2DXKV influence milk supply or can UNII-GN5XU2DXKV decrease milk supply in lactating mothers?
UNII-GN5XU2DXKV lactation summary
- DrLact safety Score for UNII-GN5XU2DXKV is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of UNII-GN5XU2DXKV may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that UNII-GN5XU2DXKV may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of UNII-GN5XU2DXKV low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using UNII-GN5XU2DXKV We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About UNII-GN5XU2DXKV usage in lactation
An Fc-peptide fusion protein that acts as an agonist in the thrombopoietin receptor stimulating platelet production.Indicated in the treatment of chronic immune thrombocytopenic purpura (ITP) when resistant to other treatments (corticoids, immunoglobulins).Administered subcutaneously once a week. Since the last update, we have not found published data on its excretion in breast milk. Its very high molecular weight makes it very unlikely that it will transfer to milk in significant quantities. Due to its protein nature it is inactivated in the gastrointestinal tract, not being absorbed, so that its oral bioavailability is practically nil, except in premature babies and the immediate neonatal period when there may be greater intestinal permeability.
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