Is Capreomycin disulfate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Capreomycin disulfate? Is Capreomycin disulfate safe for nursing mother and child? Does Capreomycin disulfate extracts into breast milk? Does Capreomycin disulfate has any long term or short term side effects on infants? Can Capreomycin disulfate influence milk supply or can Capreomycin disulfate decrease milk supply in lactating mothers?
Capreomycin disulfate lactation summary
- DrLact safety Score for Capreomycin disulfate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Capreomycin disulfate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Capreomycin disulfate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Capreomycin disulfate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Capreomycin disulfate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Capreomycin disulfate usage in lactation
Systemic absorption is minimal.
Answer by DrLact: About Capreomycin disulfate usage in lactation
Developmental problems have been reported in two infants exposed to capreomycin in breastmilk; however, their mothers were also exposed to several drugs during pregnancy and during breastfeeding, so the problems cannot necessarily be attributed to capreomycin. Because capreomycin is not orally absorbed it is unlikely to adversely affect the breastfed infant. If capreomycin is required by the mother, it is not a reason to discontinue breastfeeding.
Capreomycin disulfate Side Effects in Breastfeeding
Capreomycin was used as part of multidrug regimens to treat two pregnant women with multidrug-resistant tuberculosis, one throughout pregnancy and postpartum and the other postpartum only. The infants were breastfed (extent and duration not stated). At age 4.6 and 5.1 years, the children were developing normally except for a mild speech delay in one and hyperactivity in the other.[1]
Alternate Drugs for Drugs for treatment of Tuberculosis. ATC J04A
Cycloserine(Safe)
Isoniazid(Safe)
Pyrazinamide(Safe)
Rifampin(Safe)
Capreomycin(Low Risk)
Rifabutin(Low Risk)
Paraminosalicylic Acid(Safe)
Capreomycin Sulfate(Low Risk)
Ethambutol-Hcl(Safe)
Rifampicine(Safe)
Thioacetazone(Safe)
Amithiozone(Safe)
Ansamycin(Low Risk)
Thiosemicarbazone(Safe)