Is Methylergobasine Maleate Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Methylergobasine Maleate? Is Methylergobasine Maleate safe for nursing mother and child? Does Methylergobasine Maleate extracts into breast milk? Does Methylergobasine Maleate has any long term or short term side effects on infants? Can Methylergobasine Maleate influence milk supply or can Methylergobasine Maleate decrease milk supply in lactating mothers?
Methylergobasine Maleate lactation summary
- DrLact safety Score for Methylergobasine Maleate is 3 out of 8 which is considered Low Risk as per our analyses.
- A safety Score of 3 indicates that usage of Methylergobasine Maleate may cause some minor side effects in breastfed baby.
- Our study of different scientific research indicates that Methylergobasine Maleate may cause moderate to no side effects in lactating mother.
- Most of scientific studies and research papers declaring usage of Methylergobasine Maleate low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- While using Methylergobasine Maleate We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Methylergobasine Maleate usage in lactation
Ergot derivative which is used in the prevention and treatment of postpartum hemorrhage. It is not excreted into breast milk in clinically significant amount (Erkkola 1978) and, besides the information offered by the manufacturer, no reliable publications were found about problems in infants whose mothers were treated. There is a controversy on an antiprolactin effect and its ability to decrease milk production found by some authors (Peters 1979, Döner 1979, Weiss 1975).Some have published an association with a decreased in duration of breastfeeding though not in the percentage of initiation (Brown 2014, Jordan 2009) nor a decrease in weight gaining (Arabin 1986).Others did not find a decrease in prolactin level (Javier del Castillo 1985, Del Pozo 1975), nor difference in the rate of exclusive breastfeeding or monthly weight gain (González1984), considering that the treatments limited to the first week postpartum that use a low dose do not affect lactation or the infant. It has frequent side effects (nausea, vomiting, headache, hypertension) that do not occur with oxytocin, so the latter is preferable to reduce the risk of postpartum hemorrhage. There are insufficient data to know whether immediate breastfeeding is effective for this type of prevention (Chelmow 2011).They have occurred serious poisonings in infants when giving directly both orally or intramuscularly due to confusion with other medication for newborns (Aeby 2003).