Is Cardil Retard Safe in Breastfeeding
Question
I am a breastfeeding mother and i want to know if it is safe to use Cardil Retard? Is Cardil Retard safe for nursing mother and child? Does Cardil Retard extracts into breast milk? Does Cardil Retard has any long term or short term side effects on infants? Can Cardil Retard influence milk supply or can Cardil Retard decrease milk supply in lactating mothers?
Cardil Retard lactation summary
- DrLact safety Score for Cardil Retard is 1 out of 8 which is considered Safe as per our analyses.
- A safety Score of 1 indicates that usage of Cardil Retard is mostly safe during lactation for breastfed baby.
- Our study of different scientific research also indicates that Cardil Retard does not cause any serious side effects in breastfeeding mothers.
- Most of scientific studies and research papers declaring usage of Cardil Retard safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
- Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.
Answer by Dr. Ru: About Cardil Retard usage in lactation
It is excreted in breast milk in a clinically non-significant amount (Okada 85)Two 6 months-old breastfed twins whose mother was treated with diltiazem did not get into health problems (Lubbe 87) Evidence on other antihypertensive drugs of the same family with similar structure, pharmacokinetics and action profile (nifedipine, nimodipine, nicardipine) has shown that they are excreted into milk in non-significant amount.Diltiazem does not have any influence on prolactin production. Until more extensive published data about this drug regarding breastfeeding are available a safer alternative drug should be used, especially during the neonatal period and/or in case of premature infants. American Academy of Pediatrics: medication usually compatible with breastfeeding.
Answer by DrLact: About Cardil Retard usage in lactation
Based on limited data, amounts of diltiazem ingested by the infant are small and would not be expected to cause any adverse effects in breastfed infants.
Alternate Drugs for Anti-hypertensive Calcium channel-Blocker. ATC C08
Amlodipine(Low Risk)
Diltiazem(Safe)
Felodipine(Low Risk)
Isradipine(Low Risk)
Nifedipine(Safe)
Nimodipine(Safe)
Nisoldipine(Low Risk)
Nitrendipine(Safe)
Verapamil(Safe)
Nicardipine(Safe)
Amlodipine Besylate(Low Risk)
Verapamil Hydrochloride(Safe)
Bepridil Hydrochloride(Unsafe)
Diltiazem Hydrochloride(Safe)
Lercanidipine Hydrochloride(Low Risk)
Manidipine Hydrochloride(Low Risk)