Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-22ADO53M6F? Is UNII-22ADO53M6F safe for nursing mother and child? Does UNII-22ADO53M6F extracts into breast milk? Does UNII-22ADO53M6F has any long term or short term side effects on infants? Can UNII-22ADO53M6F influence milk supply or can UNII-22ADO53M6F decrease milk supply in lactating mothers?

UNII-22ADO53M6F lactation summary

UNII-22ADO53M6F is safe in breastfeeding
  • DrLact safety Score for UNII-22ADO53M6F is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of UNII-22ADO53M6F is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that UNII-22ADO53M6F does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of UNII-22ADO53M6F safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-22ADO53M6F usage in lactation

Phosphates are used as a laxative and to clean the bowel before medical examinations.They base their action on the little or zero amount which is absorbed (Nice 2000), causing water to escape from the intestine and severe diarrhea.Keep this in mind in order to drink as much as needed and avoid dehydration of the nursing mother who is already producing about 1 litre of liquid in the form of milk a day. Since the last update, we have not found published data on its excretion in breast milk. Both sodium and phosphate are normal components of the body and are found in breast milk at concentrations different to plasma (Allen 1991). Temporary increases in plasma phosphate levels have been observed after the administration of sodium phosphate enema (Salix 2009, Ehrenpreis 2009). It is not known whether this may affect the concentration of phosphate in breast milk, but it is believed that the variation is minimal, temporary and does not have clinical repercussions in the infant. Expert authors consider phosphate-based laxatives compatible with breastfeeding (Nice 2000).

Alternate Drugs for Blood substitutes, Perfusions, Irritgating & Electrolyte solutions. ATC B05

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