Question

I am a breastfeeding mother and i want to know if it is safe to use TX 15338? Is TX 15338 safe for nursing mother and child? Does TX 15338 extracts into breast milk? Does TX 15338 has any long term or short term side effects on infants? Can TX 15338 influence milk supply or can TX 15338 decrease milk supply in lactating mothers?

TX 15338 lactation summary

TX 15338 is safe in breastfeeding
  • DrLact safety Score for TX 15338 is 1 out of 8 which is considered Safe as per our analyses.
  • A safety Score of 1 indicates that usage of TX 15338 is mostly safe during lactation for breastfed baby.
  • Our study of different scientific research also indicates that TX 15338 does not cause any serious side effects in breastfeeding mothers.
  • Most of scientific studies and research papers declaring usage of TX 15338 safe in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About TX 15338 usage in lactation

A topical anti-fungal treatment from the imidazole family applied to the skin or vaginally. Negligible systemic absorption through the skin (Effik 2010) or vaginal mucosa (Novelli 1991) make it very unlikely that significant amounts pass into breast milk. Do not apply on nipple-areola or alternatively clean before breastfeeding. It is advisable to avoid the application to the nipple of creams, gels and other topical products containing paraffin (mineral oil) so that the infant does not absorb them (Concin 2008, Noti 2003)

Alternate Drugs for Dermatological antifungals for topical use. ATC D01

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