Question

I am a breastfeeding mother and i want to know if it is safe to use 4-Amino-5-fluoro-2(1H)-pyrimidinone? Is 4-Amino-5-fluoro-2(1H)-pyrimidinone safe for nursing mother and child? Does 4-Amino-5-fluoro-2(1H)-pyrimidinone extracts into breast milk? Does 4-Amino-5-fluoro-2(1H)-pyrimidinone has any long term or short term side effects on infants? Can 4-Amino-5-fluoro-2(1H)-pyrimidinone influence milk supply or can 4-Amino-5-fluoro-2(1H)-pyrimidinone decrease milk supply in lactating mothers?

4-Amino-5-fluoro-2(1H)-pyrimidinone lactation summary

4-Amino-5-fluoro-2(1H)-pyrimidinone is unsafe in breastfeeding
  • DrLact safety Score for 4-Amino-5-fluoro-2(1H)-pyrimidinone is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 4-Amino-5-fluoro-2(1H)-pyrimidinone may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 4-Amino-5-fluoro-2(1H)-pyrimidinone may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 4-Amino-5-fluoro-2(1H)-pyrimidinone .
  • It is recommended to evaluate the advantage of not breastfeeding while using 4-Amino-5-fluoro-2(1H)-pyrimidinone Vs not using 4-Amino-5-fluoro-2(1H)-pyrimidinone And continue breastfeeding.
  • While using 4-Amino-5-fluoro-2(1H)-pyrimidinone Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 4-Amino-5-fluoro-2(1H)-pyrimidinone usage in lactation

It is used in combination with amphotericin B. Although it is potentially toxic, no untoward effects on breastfed infants have been reported.

Alternate Drugs for Antimycotics for systemic use

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