Question

I am a breastfeeding mother and i want to know if it is safe to use 5-Fluorocytosine? Is 5-Fluorocytosine safe for nursing mother and child? Does 5-Fluorocytosine extracts into breast milk? Does 5-Fluorocytosine has any long term or short term side effects on infants? Can 5-Fluorocytosine influence milk supply or can 5-Fluorocytosine decrease milk supply in lactating mothers?

5-Fluorocytosine lactation summary

5-Fluorocytosine is unsafe in breastfeeding
  • DrLact safety Score for 5-Fluorocytosine is 5 out of 8 which is considered Unsafe as per our analyses.
  • A safety Score of 5 indicates that usage of 5-Fluorocytosine may cause serious side effects in breastfed baby.
  • Our study of different scientific research indicates that 5-Fluorocytosine may cause moderate to high side effects or may affect milk supply in lactating mother.
  • Our suggestion is to use safer alternate options rather than using 5-Fluorocytosine .
  • It is recommended to evaluate the advantage of not breastfeeding while using 5-Fluorocytosine Vs not using 5-Fluorocytosine And continue breastfeeding.
  • While using 5-Fluorocytosine Its must to monitor child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About 5-Fluorocytosine usage in lactation

It is used in combination with amphotericin B. Although it is potentially toxic, no untoward effects on breastfed infants have been reported.

Alternate Drugs for Antimycotics for systemic use

Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.