Question

I am a breastfeeding mother and i want to know if it is safe to use Tiagabine? Is Tiagabine safe for nursing mother and child? Does Tiagabine extracts into breast milk? Does Tiagabine has any long term or short term side effects on infants? Can Tiagabine influence milk supply or can Tiagabine decrease milk supply in lactating mothers?

Answer by DrLact: About Tiagabine usage in lactation

Monitor the infant for drowsiness, adequate weight gain, and developmental milestones, especially in younger, exclusively breastfed infants and when using combinations of anticonvulsant or psychotropic drugs. Because there is very limited published experience with tiagabine during breastfeeding, other agents may be preferred, especially while nursing a newborn or preterm infant.

Tiagabine Side Effects in Breastfeeding

One mother breastfed her infant while taking tiagabine 24 mg and then 20 mg daily.[1] No adverse effects were reported in 10 newborns who were 4 to 23 days old who were breastfed during maternal intake of levetiracetam 1000 to 3000 mg daily. One mother was also taking tiagabine 30 mg daily, clobazam 45 mg daily and oxcarbazepine 600 mg daily.[2]
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