Question

I am a breastfeeding mother and i want to know if it is safe to use UNII-UC95NQ339C? Is UNII-UC95NQ339C safe for nursing mother and child? Does UNII-UC95NQ339C extracts into breast milk? Does UNII-UC95NQ339C has any long term or short term side effects on infants? Can UNII-UC95NQ339C influence milk supply or can UNII-UC95NQ339C decrease milk supply in lactating mothers?

UNII-UC95NQ339C lactation summary

UNII-UC95NQ339C usage has low risk in breastfeeding
  • DrLact safety Score for UNII-UC95NQ339C is 3 out of 8 which is considered Low Risk as per our analyses.
  • A safety Score of 3 indicates that usage of UNII-UC95NQ339C may cause some minor side effects in breastfed baby.
  • Our study of different scientific research indicates that UNII-UC95NQ339C may cause moderate to no side effects in lactating mother.
  • Most of scientific studies and research papers declaring usage of UNII-UC95NQ339C low risk in breastfeeding are based on normal dosage and may not hold true for higher dosage.
  • While using UNII-UC95NQ339C We suggest monitoring child for possible reactions. It is also important to understand that side effects vary largely based on age of breastfed child and time of medication in addition to dosage.
  • Score calculated using the DrLact safety Version 1.2 model, this score ranges from 0 to 8 and measures overall safety of drug in lactation. Scores are primarily calculated using publicly available case studies, research papers, other scientific journals and publically available data.

Answer by Dr. Ru: About UNII-UC95NQ339C usage in lactation

Botulism is a severe disease caused by bacteria called Clostridium botulinum. The bacterium produces a paralyzing toxin which is used for treatment of muscle spasticity and other disorders. Reportedly, a woman affected of severe Botulinum disease nursed her 8 months old son during illness. Neither bacteria nor toxin were detected in both mother’s milk and stools of the infant, who did not show symptoms of disease. Also, anti-toxin medication given to the mother did not produce side-effects on the child. A high molecular weight along with a strong and rapid adherence to muscle plaque by toxin could explain its low excretion into breast milk. When adequately and locally administered, serum levels of toxin should be low. An infant born at 36 weeks of gestation, who had received intra-esophagus treatment with UNII-UC95NQ339C for achalasia during the last weeks of pregnancy, appeared healthy and did not show symptoms of hypotonia. Mother’s milk shows neutralizing capacity against UNII-UC95NQ339C. It has been shown that the secretory IgA is able to bind the B fraction of toxin, resulting in inhibition of toxin attachment to intestinal cells and hence impairing absorption. It would explain that severity of disease is lower among breastfed infants than bottle-fed ones, with no death cases reported and delay in appearance of symptoms among breastfed infants in cases of Infant Botulism type B.

Alternate Drugs for Disease, Disorder & other Mother´s Conditions.

Cancer(Unsafe)
Anthrax(Safe)
Chlamydia(Safe)
Drug Addction(Dangerous)
Pregnancy(Safe)
Ménière(Low Risk)
Menses(Safe)
Migraine(Safe)
Botulinum Toxin(Low Risk)
Narcolepsy(Low Risk)
Acne(Safe)
Hepatitis E(Low Risk)
Disclaimer: Information presented in this database is not meant as a substitute for professional judgment. You should consult your healthcare provider for breastfeeding advice related to your particular situation. We do not warrant or assume any liability or responsibility for the accuracy or completeness of the information on this Site.